Patent Foramen Ovale Treatment Strategies Correspond to an Index Predicting Pathogenicity

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Patent Foramen Ovale

The patent foramen ovale (PFO) is a normal interatrial communication during fetal life that persists after birth in approximately 1 of every 4 adults. PFO is a potential route for embolic transit from the systemic venous circulation to the brain. Though there is compelling circumstantial evidence implicating PFO, the precise role of PFO in the pathogenesis of cryptogenic stroke is not yet estab...

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Patent Foramen Ovale

Patent foramen ovale (PFO) is not uncommondit appears in perhaps 10% to 25% of the populationdbut only a small percent of cases will produce any clinical sequelae, such as refractory hypoxia, orthodeoxia-platypnea syndrome, or migraine headaches. PFO is most notorious, however, for its association with paradoxical embolus and cryptogenic stroke (1). Conclusive proof of a causal relationship bet...

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Patent foramen ovale.

Patent foramen ovale (PFO) is a common developmental anomaly that allows for the passage of blood and other substances from the venous to the arterial circulation. The study of PFO closure has been challenging due to widely available off-label closures performed outside the clinical trial setting. To date, no study has demonstrated benefit of closure using intention-to-treat analyses. Secondary...

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Background—A causal relationship between patent foramen ovale (PFO) and migraine has been hypothesized, and improvement of migraine frequency and severity after percutaneous PFO closure has been reported. Population-based data on the relationship between PFO and migraine are sparse, however. The objective of this study was to examine the association between PFO and migraine among stroke-free in...

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ژورنال

عنوان ژورنال: Cureus

سال: 2019

ISSN: 2168-8184

DOI: 10.7759/cureus.4778